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Committee Established: 1995

Committe Type: Board Appointed

Research Advisory Committee

Duties and Responsibilities

Overview
The Research Advisory Committee (RAC or Committee) is appointed by the NCA Board and is accountable directly to the NCA Board. The RAC works in close contact with but is independent of the Newfoundland Health Challenge (NHC) and the Health and Longevity Committee with respect to reporting to the NCA Board. The RAC comprises the NCA’s scientific resources and is instrumental in providing review and feedback regarding potential and active NCA supported research projects, as well as opening and maintaining lines of communications within the research community. The RAC Chairperson, if appointed by the Board, may also serve as the AKC Canine Health Foundation (CHF) liaison, as delineated in the NHC operating procedures, and, as such, would fulfill the responsibilities of both positions.
Duties and Responsibilities
• Reviews research proposals for relevance to Newfoundland health priorities
• Advises NCA Board regarding merit of proposals to receive NCA funding
• Maintains active communications between NCA, funding agencies and researchers involved with NCA supported projects
• Monitors the progress of NCA supported projects to measure whether schedules of deliverables are being met satisfactorily within approved findinglevels
• Describes funded studies and reports progress of ongoing studies to membership by means of regular articles in Newf Tide
• Assists researchers in recruiting subjects to participate in NCA supported studies when appropriate by placing appeals in Newf Tide
• Prepares an annual report for publication in Newf Tide
• Prepares and submits an annual budget to the NCA Treasurer

History & Board Actions

V27.1 11/05/95
Newfoundland Research Advisory Committee established. Committee will consist of highly qualified expert Club Members and be directly accountable to the Board. The
Committee will be charged with providing guidance to the Board on proposed research projects before a commitment is made to participate in a project and dedicate NCA
resources. Committee would provide due diligence on proposed projects and continual oversight, evaluation and guidance to the Board on projects it authorizes. Formal
Committee responsibilities to be established.
V30.1 11/01/98
Board approves Committee responsibilities/procedures as follows:
Operating Procedure
Working with funding agencies such as the CHF, the Morris Animal Foundation (MAF), and the NCA Health and Longevity Committee, the RAC initiates contacts and identifies research proposals directly relevant to the health interests of the Newfoundland. Proposals submitted directly to the Committee are reviewed for relevance and returned to the principal investigator with a note regarding NCA interest or lack of thereof and with the suggestion that the proposal be submitted to a funding agency where it can be subjected to peer review. If a proposal is relevant and is approved by the agency, the Committee will advise the NCA Board of Directors of its recommendation for full, partial, or no NHC funding. The RAC will also keep the Board apprised of proposals returned to funding agencies/researchers where it has not recommended NCA involvement. The Committee will inform funding agencies of our research priorities and willingness to participate in projects. When a health priority is not being addressed by current proposals, the Committee may send notices to veterinary schools advising them of our interest and recommending that interested researchers submit relevant proposals to funding agencies that we work with. It is the responsibility of the Chairman to inform the RAC members when there are proposals to review and to make available copies of appropriate materials and reports. Project progress reports will be reviewed and the Committee will regularly report this progress to the Membership of NCA by means of articles in Newf Tide.
V30.1 08/25/98 (Teleconference)
Board accepts the recommendation of the Research Advisory Committee to provide partial funding ($1,200) for the research project “Mediodistal to Lateroproximal Radiographic View for Early Diagnosis of Fragmentation of the Medial Coronoid Process in Dogs”. The balance of the $13,310 budget for the study to be conducted at North Carolina State University by principal investigator Denis Marcellin-Little will be provided by the AKC Canine Health Foundation and several other parent clubs.
V30.3 03/24/99
Board approves RAC recommendation to financially support the Michigan State University proposal “Determination of the Mode of Inheritance of a Forelimb Anomaly in Newfoundlands”.
V31.1 10/05/99 (Teleconference)
Board approves RAC recommendation not to financially support AKC CHF proposal to investigate the genetics of Canine Hip Dysplasia (would not adequately address the diagnostic criteria for Hip Dysplasia). RAC requested AKC CHF’s request for a Forelimb (Elbow) Anomaly Study proposal be a priority.
V31.2 12/26/99
Board recommends approval of “Mapping of a gene of canine subaortic stenosis”, Oregon Health Science Univ., $2500 per year for three years. Board establishes position of Newfoundland Health Liaison to facilitate communication
between health challenge, research advisory committee and health and longevity committee.
V32.1 9/26/00
Board recommends approval of grants: “Development of a DNA based test for forelimb anomaly in Newfoundlands”, Michigan State Univ., $1250; “Anchoring the canine map
through BAC mapping”, Fred Hutchinson Cancer Research Center, $2500 per year for three years; and “Development of PCR multiplexed canine marker panels for the purpose of genome screening and linkage analysis”, Univ. of California, $2500 per year for three years.
V32.1 11/3/00
Board recommends approval of grant: “The molecular cytogenetics of canine lymphosarcoma: correlating chromosomal changes with clinical disease”, $1400 year one and $1600 year two.
V35.3 5/27/04
Recommend to the NCA Charitable Trust the funding of the following three research projects as recommended by the RAC:
• CHF #0212: Development of a New Resource for Positioning Cloning of Hip Dysplasia Genes: A High Density SNP Map of Canine Chromosome One (Elaine Ostrander, PhD, Fred Hutchison, Cancer Research Center, total cost$100,000,
NCA’s share $2,500 per years for two years}.
CHF #0247: The Study of the Genetics of Cranial Cruciate Ligament Disease in the Dog (Max Rothchild, Iowa State University, total cost $96,392, NCA’s share $2,500 per year for two years).
• CHF #0272: Oligonucleotide Microarray Gene Expression Profiling of Canine Lymphoma (William Kisseberth, Ohio State University, total cost $90,000, NCA’s share $2,500 for two years).

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